0351918

A1 19900124

EP0351918

19900124

A61K31/34 C07D309/30

A61K 31/ 365 A I

A61K 31/ 366 A I

A61P 3/ 06 A I

C07B 63/ 00 A I

C07C 69/ 28 A I

C07D 309/ 30 A I

07 D

309

89201879

EP19890201879

19890717

89201879

US19880221475

19880719

221475

MERCK & CO INC [US]

MERCK & CO. INC

TREIBER LASZLO R

TREIBER, LASZLO R

Process for the lactonization of mevinic acids and analogs thereof.

Verfahren zur Lactonisierung von Mevinsäuren und deren Analogen.

Procédé pour la lactonisation d'acides méviniques et leurs analogues.

EP0183132

0183132

EP0232997

0232997

A CHEMICAL ABSTRACTS, vol. 108, no. 5, February 1, 1988, Columbus, Ohio, USA LYNN, J.E. et al. "Synthesis of an HMG-CoA reductase in- hibitor: a diastereoselective aldol approach" page 598, column 2, Abstract-no. 37 475h A

A process for the lactonization of mevinic acid HMG-CoA reductase inhibitors and analogs thereof is disclosed.